Show Notes
This release contains only the music track from Base by Base Episode 358.
Song title: Import the Light Back In
Original Base by Base episode: 358: CHCHD4 and a Pediatric OXPHOS Collapse
Article metadata:
Article title: Biallelic variants in CHCHD4 are associated with combined OXPHOS defect leading to mitochondrial disease
Journal: Human Genetics and Genomics Advances
DOI: 10.1016/j.xhgg.2026.100615
Reference: Mantecon M, Chhuon C, Roger K, et al. Biallelic variants in CHCHD4 are associated with combined OXPHOS defect leading to mitochondrial disease. Human Genetics and Genomics Advances. 2026;7:100615. doi:10.1016/j.xhgg.2026.100615
Lyrics:
Verse 1
Midnight in the lab, the monitors glow
A tiny spark is fading way down below
Powerhouse rooms with the doors half-shut
Engines that stutter when they should just run
Pre-Chorus
We trace the break in a hidden line
Two copies wrong, and the whole grid declines
But if we can carry the missing part
We can restart, we can restart
Chorus
Bring the light back in, through the inner door
Let the proteins find what they came here for
When the turbines fail and the breath runs thin
Bring the light back in, bring the light back in
Verse 2
Cargo at the edge, it’s waiting in the dark
Signals like whispers, trying to spark
Complex I, Complex IV fall out of time
Pieces won’t settle, the build won’t align
Bridge
Not just a number on a gene report page
It’s a map to the fault, it’s a key to the cage
Send the wild-type through—watch the current return
From silence to motion, from cold to burn
Final Chorus
Bring the light back in, through the inner door
Let the broken assembly rise to the roar
When the chain lets go and the night caves in
Bring the light back in, bring the light back in
