Show Notes
This release contains only the music track from Base by Base Episode 340.
Song title: Four Letters, Eight Roads
Original Base by Base episode: 340: Microexon Control of Behavior — PTPRD Splicing
Article metadata:
Article title: Alternative microexon splicing code for a four - amino acid peptide of PTPRD governs behavioral development
Journal: Proceedings of the National Academy of Sciences (PNAS)
DOI: 10.1073/pnas.2515310123
Reference: Imai A, Izumi H, Ito N, et al. Alternative microexon splicing code for a four-amino acid peptide of PTPRD governs behavioral development. Proc Natl Acad Sci U S A. 2026;123(15):e2515310123. doi:10.1073/pnas.2515310123
Lyrics:
Verse 1
In the quiet of a growing mind,
A tiny cut decides the kind—
Four letters slipped in, four left behind,
And circuits learn their turn in time.
Pre-Chorus
A hidden switch beneath the seam,
Turns ratios into lived-out dreams;
Not how much, but how it’s split,
Makes every signal choose its fit.
Chorus
Four letters, eight roads, one brain in bloom,
Skips like lightning, lands like a tune;
When the balance bends, the whole world shows—
We are the splice, we are the glow.
Verse 2
One small enhancer, pulling it near,
Keeps the stitch when the days are clear;
Cut it out and the steps feel wrong,
Learning stumbles where it belonged.
Bridge
Then activity hits—within an hour,
The pattern flips, a sudden power;
Too fixed, too full, no room to breathe,
And distant memories start to leave.
Final Chorus
Four letters, eight roads, set by the code,
A living map in a shifting load;
Hold the middle, let it flow—
We are the splice, we are the glow.